acetylsalicylic acid in acid solution
acetylsalicylic acid in neutral and basic solution
Keeping the acetylsalicylic acid in ionic form or preventing it from dissolving until it reached the small intestine would prevent it from causing bleeding. Some manufacturers have tried to add buffering agents to their tablets for this purpose. But the benefits of buffered aspirin are disputed.
Just about any buffering agent used in an antacid can be used in buffered aspirin. Bufferin, for example, uses MgO. Other preparations use CaCO3.
Author: Fred Senese firstname.lastname@example.org
Copyright © 1997-2010 by Fred Senese
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Last Revised 08/17/15.URL: http://antoine.frostburg.edu/chem/senese/101/acidbase/faq/print-buffered-aspirin.shtml